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Basic science lab professionals

Dr. BenjaminJohn T. Benjamin, M.D., M.P.H.
Dr. Benjamin's research interests are in understanding why early pulmonary inflammation alters lung development leading to bronchopulmonary dysplasia (BPD) in preterm infants.  As a primary focus, his laboratory uses mouse models and tissue culture systems to study how antenatal infections and inflammation primes the neonatal lung to second "hit" injuries such as hyperoxia and mechanical ventilation.

 

Susan GuttantagSusan H. Guttentag, M.D.
Dr. Guttentag is Director of the Division of Neonatology. Her research is in the area of lung cell biology, specifically in the production, assembly, and secretion of pulmonary surfactant from the alveolar epithelial type 2 cells. Her work currently involves understanding the cellular trafficking pathways necessary to deliver surfactant-specific components to the surfactant storage organelles known as lamellar bodies.

 

Jennifer Herington

Jennifer L. Herington, Ph.D.
Dr. Herington's research involves over a decade of training in reproductive physiology focused on understanding the endometrial changes necessary for successful onset and maintenance of pregnancy, as well as the impact of inflammation on pregnancy outcomes. Specifically, her expertise includes embryo implantation, and inflammation-driven dysfunctional endometrial phenotypes and perinatal development.
Learn more about Dr. Herington's research and the Pre3 Initiative.

Dr. PariaBibhash C. Paria, Ph.D.
Dr. Paria's work focuses on embryonic and uterine signals in mammalian embryo development and implantation. Current projects include the role of histamine in embryo development and implantation, signaling molecules involved in the initiation of progesterone-dependent implantation in hamsters and the mechanisms of protection of the implanting embryo from maternal dangers.
Learn more about Dr. Paria's research.

Dr PlosaErin Jean Plosa, M.D.
Dr. Plosa's work is focused on the interaction between the extracellular matrix and airway epithelial cells during lung development. She uses a mouse model to investigate the role of integrins during lung branching morphogenesis and alveolarization.

 

Dr ReeseJohn Jeffrey Reese, M.D.
Dr. Reese's research interests include regulation of embryo implantation, mechanisms of term and pre-term labor, prostaglandin biology, and regulation of the ductus arteriosus.
Learn more about Dr. Reese's research

 

Elaine SheltonElaine L. Shelton, Ph.D.
Dr. Shelton is interested in understanding blood vessel development and identifying other non-vascular cell types that can be used to form new vasculature or repair injured vessels.
Learn more about Dr. Shelton's research.

 

Dr. StahlmanMildred T. Stahlman, M.D.
Dr. Stahlman has a long-term interest in the role of retinoids in lung development, lung injury and repair. Her research, in collaboration with Dr. Jeffrey Whitsett, focuses primarily on the expression patterns of the surfactant apoproteins and the role of ABCA3 in the pathogenesis of acute and chronic lung disease. Dr. Stahlman's expertise in microscopic analysis of the lung, at both the light and electron microscopic levels, has resulted in the development of strong collaborative efforts with a number of investigators throughout the country.

Dr SucreJennifer Sucre, M.D.
Dr. Sucre's research focuses on human lung development and how perturbations of normal lung development give rise to neonatal lung diseases, particularly bronchopulmonary dysplasia. To answer these questions, she is currently developing 3-dimensional human models of the developing lung and BPD, with a goal of using these models to identify therapeutic targets and to screen for novel therapeutic agents.

 

Dr. WeitkampJörn Hendrik Weitkamp, M.D.
Dr. Weitkamp's current laboratory efforts focus on the development of immune regulation in the premature intestine and its role in necrotizing enterocolitis (NEC), the most common and devastating gastrointestinal emergency in premature infants. Specifically, he studies the development and function of FoxP3-positive regulatory T cells and TCRgd intraepithelial lymphocytes isolated from blood and surgical tissue sections from infants with and without NEC. Through discovery of immunological mechanisms in the premature human intestinal tract and how they are affected by nutrition and bacterial colonization, Dr. Weitkamp expects to identify novel cellular and molecular targets for therapy and prevention of NEC and other inflammation-mediated complications of prematurity. 
Learn more about Dr. Weitkamp's research.



 
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Monroe Carrell Jr. Children's Hospital at Vanderbilt